NEURONAL ACTIVATION MODULATES ENHANCER ACTIVITY OF GENES FOR EXCITATORY SYNAPTOGENESIS THROUGH DE NOVO DNA METHYLATION

Neuronal activation modulates enhancer activity of genes for excitatory synaptogenesis through de novo DNA methylation

Post-mitotic neurons do exhibit DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged.While the mechanism and physiological significance of DNA demethylation in neurons have been extensively elucidated, the occurrence of de novo DNA methylation ar-13995n

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Estimation of Photovoltaic Hosting Capacity Due to the Presence of Diverse Harmonics in an Active Distribution Network

Renewable distributed energy resources are the solution to rising power demand, but their integration is a difficult technological undertaking that requires careful planning.Distributed energy resources are mostly incorporated in the final level of power system networks, where harmonic content swings are highest.At the planning stage, the highest p

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Chirality transitions in a system of active flat spinners

We ar-13995n study in this work the two-dimensional dynamics of an experimental system of disk-shaped rotors, fluidized by turbulent upflow.Contrary to previous knowledge, our experiments show the same particle chiral geometry can produce flows with different chiralities.In particular, we unveil a conspicuous complex chiral flow which displays mult

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Active particles in geometrically confined viscoelastic fluids

We experimentally study the dynamics of active particles (APs) in a viscoelastic fluid under various geometrical constraints such as flat walls, spherical obstacles and cylindrical cavities.We observe that the main effect of the confined viscoelastic fluid is to induce an effective repulsion on the APs when moving close to a rigid surface, which de

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